What tool is used for penicillin allergy risk assessment?

• A. Liverpool Scale
• B. Beers Criteria
• C. Naranjo Adverse Drug Reaction Scale
• D. PEN-FAST Scoring System

Answer: (D)

The main idea is to accurately stratify penicillin allergy risk based on a focused history so clinicians can decide who can safely be re-exposed to penicillin. The PEN-FAST scoring system is built specifically for this purpose. It uses simple questions about the patient's past penicillin reactions and timing to assign a risk level. A low PEN-FAST score suggests the reported allergy is unlikely to be a true IgE-mediated allergy, making a supervised oral penicillin challenge a reasonable next step and potentially removing an unnecessary label. A higher score indicates greater risk and may lead to skin testing or choosing alternative antibiotics.

This is why the PEN-FAST tool is the best answer: it is purpose-built for penicillin allergy risk assessment and has practical clinical utility in guiding safe re-exposure. The other tools mentioned are not designed for penicillin-specific risk stratification; they serve different purposes in pharmacovigilance or medication safety and are not used to determine suitability for penicillin challenge.