Drug-induced liver injury accounts for 14% of acute liver failure cases excluding acetaminophen.

• A. 14%
• B. 5%
• C. 25%
• D. 40%

Answer: (A)

Think about how acute liver failure is usually caused. Acetaminophen overdose is the dominant cause overall, so when you remove those cases, the remaining share caused by drug-induced liver injury is smaller. The figure that matches this non-acetaminophen portion is about 14%, which is a commonly cited epidemiologic estimate for DILI as a cause of acute liver failure after excluding acetaminophen. The other percentages would misrepresent the relative contribution: they’re either too low to reflect DILI’s role once acetaminophen is removed, or too high given how large acetaminophen toxicity remains in ALF. So 14% best fits the typical distribution and explains the statement.